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View larger JNJ-39758979
AT11723L
CAS 1046447-90-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.85 | Total: $259.25 |
| 1 | 10 | $43.92 | Total: $439.20 |
| 1 | 25 | $37.21 | Total: $930.25 |
| 1 | 50 | $31.72 | Total: $1,586.00 |
| 1 | 100 | $27.45 | Total: $2,745.00 |
Data sheet
| Molecular Formula | C11H19N5 |
| Molecular Weight | 221.3 |
| CAS Numbers | 1046447-90-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1 |
| References | Savall BM, et al. Discovery and SAR of 6-alkyl-2,4-diaminopyrimidines as histamine H? receptor antagonists. J Med Chem. 2014 Mar 27;57[6] 2429-39. |
More info
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells.