Hydroxylases

Osilodrostat View larger

Osilodrostat

AT4277

CAS 928134-65-0

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$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC13H10FN3
Molecular Weight227.24
CAS Numbers928134-65-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1cc(ccc1[C@H]1CCc2cncn12)C#N
ReferencesLi L, et al. Osilodrostat [LCI699], a potent 11?-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide A 13-week study in rats. Toxicol Appl Pharmacol. 2015 Aug 1;286[3] 224-33.

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Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11?-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).