Hydroxylases

MK-8617 View larger

MK-8617

AT4106

CAS 1187990-87-9

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC24H21N5O4
Molecular Weight443.45
CAS Numbers1187990-87-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc(cc1)C(NC(=O)c1cnc([nH]c1=O)-c1cccnn1)c1ccc(OC)cc1
ReferencesJohn S. Debenham, et al. J Med Chem. 2016, 59 [24] 11039-11049.

More info

MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD123 (IC50: 1.01.014 nM).