Hydroxylases

ML228 View larger

ML228

AT7836

CAS 1357171-62-0

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC27H21N5
Molecular Weight415.49
CAS Numbers1357171-62-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(Nc1nc(nnc1-c1ccccc1)-c1ccccn1)c1ccc(cc1)-c1ccccc1
ReferencesTheriault JR, et al. Discovery of a Small Molecule Activator of the Hypoxia Inducible Factor Pathway. Probe Reports from the NIH Molecular Libraries Program.

More info

ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 ?M. ML228 potently activates HIF in vitro as well as its downstream target VEGF.