Hydroxylases

p-Fluoro-L-phenylalanine View larger

p-Fluoro-L-phenylalanine

AT41274

CAS 1132-68-9

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Data sheet

Molecular FormulaC9H10FNO2
Molecular Weight183.18
CAS Numbers1132-68-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN[C@@H](Cc1ccc(F)cc1)C(O)=O
ReferencesLuck LA, et al. Fluorescence and 19F NMR evidence that phenylalanine, 3-L-fluorophenylalanine and 4-L-fluorophenylalanine bind to the L-leucine specific receptor of Escherichia coli. Protein Sci. 2000;9[12] 2573-2576.

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p-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that can be used to study the regulation of that enzyme. p-Fluoro-L-phenylalanine binds to the L-leucine specific receptor of Escherichia coli with an KD of 0.26 ?M.