Array
(
)
1
> Cytokine Receptors>IL Receptors>IRAK-IN-6

IL Receptors

IRAK-IN-6 View larger

IRAK-IN-6

AOB9600

CAS: 1042672-97-8

 

Chemical Name: IRAK Inhibitor-6; N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide

More details

100 Items

Molarity Calculation Cart®

HOW TO ORDER

$37.50

$37.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.88 Total: $159.38
110 $27.00 Total: $270.00
125 $22.88 Total: $571.88
150 $19.50 Total: $975.00
1100 $16.88 Total: $1,687.50

Data sheet

Molecular FormulaC20H20N4O3S
Molecular Weight396.46
CAS Numbers1042672-97-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO Aqueous
Purity95% by HPLC
SynonymIRAK-IN-6; IRAK IN 6; IRAKIN6; IRAK inhibitor 6
IUPAC/Chemical NameN-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
InChl KeyJQSRUVXPODZKAF-UHFFFAOYSA-N
InChl CodeInChI=1S/C20H20N4O3S/c1-26-18-11-15(24-7-9-27-10-8-24)4-5-16(18)22-19(25)17-13-28-20(23-17)14-3-2-6-21-12-14/h2-6,11-13H,7-10H2,1H3,(H,22,25)
SMILES CodeO=C(C1=CSC(C2=CC=CN=C2)=N1)NC3=CC=C(N4CCOCC4)C=C3OC
References1) Dudhgaonkar S, et al. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity. J Immunol. 2017 Feb 1;198(3):1308-1319.

2) Marinho FV, et al, Oliveira SC. Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection. J Immunol. 2016 Sep 1;197(5):1852-63.

More info

Novel interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor