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IRAK-IN-6
AOB9600
CAS: 1042672-97-8
Chemical Name: IRAK Inhibitor-6; N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $16.88 | Total: $1,687.50 |
| 1 | 50 | $19.50 | Total: $975.00 |
| 1 | 25 | $22.88 | Total: $571.88 |
| 1 | 10 | $27.00 | Total: $270.00 |
| 1 | 5 | $31.88 | Total: $159.38 |
Data sheet
| Molecular Formula | C20H20N4O3S |
| Molecular Weight | 396.46 |
| CAS Numbers | 1042672-97-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO Aqueous |
| Purity | 95% by HPLC |
| Synonym | IRAK-IN-6; IRAK IN 6; IRAKIN6; IRAK inhibitor 6 |
| IUPAC/Chemical Name | N-[2-Methoxy-4-(4-morpholinyl)phenyl]-2-(3-pyridinyl)-4-thiazolecarboxamide |
| InChl Key | JQSRUVXPODZKAF-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H20N4O3S/c1-26-18-11-15(24-7-9-27-10-8-24)4-5-16(18)22-19(25)17-13-28-20(23-17)14-3-2-6-21-12-14/h2-6,11-13H,7-10H2,1H3,(H,22,25) |
| SMILES Code | O=C(C1=CSC(C2=CC=CN=C2)=N1)NC3=CC=C(N4CCOCC4)C=C3OC |
| References | 1) Dudhgaonkar S, et al. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity. J Immunol. 2017 Feb 1;198(3):1308-1319. 2) Marinho FV, et al, Oliveira SC. Lack of IL-1 Receptor-Associated Kinase-4 Leads to Defective Th1 Cell Responses and Renders Mice Susceptible to Mycobacterial Infection. J Immunol. 2016 Sep 1;197(5):1852-63. |
More info
Novel interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor