IL Receptors

CP 424174 View larger

CP 424174

AT8828

CAS 210825-31-3

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$34.00

$34.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.30 Total: $1,530.00
150 $17.68 Total: $884.00
125 $20.74 Total: $518.50
110 $24.48 Total: $244.80
15 $28.90 Total: $144.50

Data sheet

Molecular FormulaC22H29ClN2O4S
Molecular Weight452.99
CAS Numbers210825-31-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cccc(c1)C(C)(C)O
ReferencesPerregaux D G , Mcniff P , Laliberte R , et al. Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors.[J]. Journal of Pharmacology & Experimental Therapeutics, 2001, 299[1] 187.

More info

CP 424174 is an inhibitor of IL-1? post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1?. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.