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View larger E7820
AOB37385
CAS: 289483-69-8
Chemical Name: NSC-719239; 3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Data sheet
| Molecular Formula | C17H12N4O2S |
| Molecular Weight | 336.37 |
| CAS Numbers | 289483-69-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | E7820; E-7820; E 7820. |
| IUPAC/Chemical Name | N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide |
| InChl Key | LWGUASZLXHYWIV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H12N4O2S/c1-11-5-6-15(17-16(11)13(9-19)10-20-17)21-24(22,23)14-4-2-3-12(7-14)8-18/h2-7,10,20-21H,1H3 |
| SMILES Code | O=S(C1=CC=CC(C#N)=C1)(NC2=CC=C(C)C3=C2NC=C3C#N)=O |
| References | 1) Ito K, et al. Enhanced anti-angiogenic effect of E7820 in combination with erlotinib in epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer xenograft models. Cancer Sci. 2014 Aug;105(8):1023-31. doi: 10.1111/cas.12450. PubMed PMID: 24841832. 2) Geramizadeh B, Asadian F, Taghavi A. Esophageal melanocytosis in oral opium consumption. Iran Red Crescent Med J. 2014 Jan;16(1):e7820. doi: 10.5812/ircmj.7820. Epub 2014 Jan 5. PubMed PMID: 24719715; PubMed Central PMCID: PMC3964433. |
More info
Novel inhibitor of integrin alpha 2, inducing proteasomal degradation of the U2AF-related splicing factor coactivator of activating protein-1 and estrogen receptors (CAPERa) via CRL4(DCAF15) mediated ubiquitination in human cancer cell lines