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View larger Cilengitide
AT2494
CAS 188968-51-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $32.30 | Total: $161.50 |
| 1 | 10 | $27.36 | Total: $273.60 |
| 1 | 25 | $23.18 | Total: $579.50 |
| 1 | 50 | $19.76 | Total: $988.00 |
| 1 | 100 | $17.10 | Total: $1,710.00 |
Data sheet
| Molecular Formula | C27H40N8O7 |
| Molecular Weight | 588.66 |
| CAS Numbers | 188968-51-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O |
| References | Hariharan S, et al. Assessment of the biological and pharmacological effects of the alpha nu beta3 and alpha nu beta5 integrinreceptor antagonist, Cilengitide [EMD 121974], in patients with advanced solid tumors. Ann Oncol. 2007 Aug;18[8] 1400-7. |
More info
Cilengitide (EMD 121974) is a potent integrin inhibitor for the ?v?35 receptor (IC50: 4.179 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.