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View larger Bexotegrast
AT39933
CAS 2376257-44-0
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $90.10 | Total: $450.50 |
| 1 | 10 | $76.32 | Total: $763.20 |
| 1 | 25 | $64.66 | Total: $1,616.50 |
| 1 | 50 | $55.12 | Total: $2,756.00 |
| 1 | 100 | $47.70 | Total: $4,770.00 |
Data sheet
| Molecular Formula | C27H36N6O3 |
| Molecular Weight | 492.61 |
| CAS Numbers | 2376257-44-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4 |
| References | Anindya Roy, et al. De novo design of highly selective miniprotein inhibitors of integrins ?v?6 and ?v?8. Nat Commun. 2023 Sep 13;14[1] 5660. |
More info
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of ?v?6 and ?v?1 integrins with antifibrotic effects, inhibiting ?v?6 and ?v?1-induced activation of TGF-?. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP).