KCC2 - K-Cl co-transporter

Sematilide hydrochloride View larger

Sematilide hydrochloride

AT3574

CAS 101526-62-9

More details

Molarity Calculation Cart®

HOW TO ORDER

$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC14H24ClN3O3S
Molecular Weight349.87
CAS Numbers101526-62-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.CCN(CC)CCNC(=O)c1ccc(NS(C)(=O)=O)cc1
ReferencesYoshida H,et al. Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model. Circ J. 2002 Aug;66[8] 758-62.

More info

Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration.