KCC2 - K-Cl co-transporter

IPN60090 View larger

IPN60090

AT11412

CAS 1853164-83-6

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$91.00

$91.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $40.95 Total: $4,095.00
150 $47.32 Total: $2,366.00
125 $55.51 Total: $1,387.75
110 $65.52 Total: $655.20
15 $77.35 Total: $386.75

Data sheet

Molecular FormulaC24H27F3N8O3
Molecular Weight532.52
CAS Numbers1853164-83-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1
ReferencesMaria Emilia Di Francesco, et al. Gls1 inhibitors for treating disease. WO2016004404A2.

More info

IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulantimmunomodulatory activity, selectively targets, binds, and inhibits human glutaminase, and can be used to study GLS1-mediated diseases.