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KCC2 - K-Cl co-transporter
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View larger Gut restricted-7
AT11515
CAS 2553218-46-3
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $113.05 | Total: $565.25 |
| 1 | 10 | $95.76 | Total: $957.60 |
| 1 | 25 | $81.13 | Total: $2,028.25 |
| 1 | 50 | $69.16 | Total: $3,458.00 |
| 1 | 100 | $59.85 | Total: $5,985.00 |
Data sheet
| Molecular Formula | C25H40FNaO6S |
| Molecular Weight | 510.64 |
| CAS Numbers | 2553218-46-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(CF)=O)C)([H])[C@@]4([C@](C[C@@H](CC4)OS(=O)([O-])=O)([H])C1)C.[Na+] |
| References | Adhikari AA, et al. Development of a covalent inhibitor of gut bacterial bile salt hydrolases. Nat Chem Biol. 2020 Mar;16[3] 318-326. |
More info
Gut restricted-7 (GR-7) is a covalent and orally active pan-bile salt hydrolase (BSH) inhibitor that reduces gut bacterial BSHs and decreases deconjugated bile acid levels in the feces of mice.