KCC2 - K-Cl co-transporter

WAY-213613 hydrochloride View larger

WAY-213613 hydrochloride

AT13330

CAS 2450268-84-3

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$46.00

$46.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $20.70 Total: $2,070.00
150 $23.92 Total: $1,196.00
125 $28.06 Total: $701.50
110 $33.12 Total: $331.20
15 $39.10 Total: $195.50

Data sheet

Molecular FormulaC16H14BrClF2N2O4
Molecular Weight451.65
CAS Numbers2450268-84-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeBrC(C=C(F)C(F)=C1)=C1OC2=CC=C(NC(C[C@H](N)C(O)=O)=O)C=C2.Cl
ReferencesDunlop J, et al. Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAATMol Pharmacol. 2005 Oct;68[4] 974-8Epub 2005 Jul 13.

More info

WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].