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View larger GW 542573X
AT22826
CAS 660846-41-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $39.10 | Total: $195.50 |
| 1 | 10 | $33.12 | Total: $331.20 |
| 1 | 25 | $28.06 | Total: $701.50 |
| 1 | 50 | $23.92 | Total: $1,196.00 |
| 1 | 100 | $20.70 | Total: $2,070.00 |
Data sheet
| Molecular Formula | C19H28N2O5 |
| Molecular Weight | 364.44 |
| CAS Numbers | 660846-41-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(OCC1CCN(C(OC(C)(C)C)=O)CC1)=O)C2=C(OC)C=CC=C2 |
| References | Hougaard C, et al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-[2-methoxyphenylcarbamoyloxymethyl]-piperidine-1-carboxylic acid tert-butyl ester [GW542573X] is dependent on serine 293 in the S5 segment. Mol Pharmacol. 2009;76[3] 569-578. |
More info
GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.GW 542573X induces a leftward shift in the Ca2+ response curve of hSK1 from an EC50 (Ca2+) value of 410 nM to 240 nM, which can be used to study neurological disorders.