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KCC2 - K-Cl co-transporter
- Protein Control Ligand
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View larger SLC26A3-IN-1
AT72054
CAS 307552-53-0
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Data sheet
| Molecular Formula | C23H18O4 |
| Molecular Weight | 358.39 |
| CAS Numbers | 307552-53-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(O)(=O)C=1C=2C(OC1C3=CC=CC=C3)=CC=C(OCC4=C(C)C=CC=C4)C2 |
| References | Cil O, et al. Small molecule inhibitors of intestinal epithelial anion exchanger SLC26A3 [DRA] with a luminal, extracellular site of action. Eur J Med Chem. 2023;249 115149. |
More info
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM. SLC26A3, a solute carrier (SLC) protein and member of the SLC26 family, exhibits a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate. Downregulated in adenomas (DRA), SLC26A3 is involved in intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea.