KCC2 - K-Cl co-transporter

JNJ303 View larger

JNJ303

AOB33455

CAS No: 878489-28-2

 

Chemical Name: AC-1; 2-(4-Chloro-phenoxy)-N-(5-methanesulfonylamino-adamantan-2-yl)-2-methyl-propionamide

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$15.00

$15.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $6.75 Total: $675.00
50 $7.80 Total: $390.00
25 $9.15 Total: $228.75
10 $10.80 Total: $108.00
5 $12.75 Total: $63.75

Data sheet

Molecular FormulaC21H29ClN2O4S
Molecular Weight440.98
CAS Numbers878489-28-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymJNJ303; JNJ-303; JNJ 303; AC-1; AC 1; AC1;
IUPAC/Chemical Name2-(4-Chloro-phenoxy)-N-(5-methanesulfonylamino-adamantan-2-yl)-2-methyl-propionamide
InChl KeyOSGIRCJRKSAODN-UHFFFAOYSA-N
InChl CodeInChI=1S/C21H29ClN2O4S/c1-20(2,28-17-6-4-16(22)5-7-17)19(25)23-18-14-8-13-9-15(18)12-21(10-13,11-14)24-29(3,26)27/h4-7,13-15,18,24H,8-12H2,1-3H3,(H,23,25)
SMILES CodeCC(C)(OC1=CC=C(Cl)C=C1)C(NC2C3CC4CC(C3)(NS(=O)(C)=O)CC2C4)=O
References1) Altomare C, et al. Human-induced pluripotent stem cell-derived cardiomyocytes from cardiac progenitor cells: effects of selective ion channel blockade. Europace. 2016 Dec;18(suppl 4):iv67-iv76.

2) Wrobel E, et al. KCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targeting. Nat Commun. 2016 Oct 12;7:12795.

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Novel specific inhibitor of heteromeric Kv7.1/KCNE1 channel complexes in a concentration- and time-dependent manner

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