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Nedisertib (M-3814)
AOB33363
CAS: 1637542-33-6
Chemical Name: MSC2490484A; (S)-(2-chloro-4-fluoro-5-(7-morpholinoquinazolin-4-yl)phenyl)(6-methoxypyridazin-3-yl)methanol
This product is discontinued for commercial reason.
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $0.00 | Total: $0.00 |
| 1 | 50 | $0.00 | Total: $0.00 |
| 1 | 25 | $0.00 | Total: $0.00 |
| 1 | 10 | $0.00 | Total: $0.00 |
| 1 | 5 | $0.00 | Total: $0.00 |
Data sheet
| Molecular Formula | C24H21ClFN5O3 |
| Molecular Weight | 481.91 |
| CAS Numbers | 1637542-33-6 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | MSC2490484A; MSC-2490484A; MSC 2490484A; M3814; M-3814; M 3814; nedisertib |
| IUPAC/Chemical Name | (S)-(2-chloro-4-fluoro-5-(7-morpholinoquinazolin-4-yl)phenyl)(6-methoxypyridazin-3-yl)methanol |
| InChl Key | MOWXJLUYGFNTAL-DEOSSOPVSA-N |
| InChl Code | InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3/t24-/m0/s1 |
| SMILES Code | COC1=CC=C([C@@H](O)C2=CC(C3=C(C=CC(N4CCOCC4)=C5)C5=NC=N3)=C(F)C=C2Cl)N=N1 |
| References | Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900 |
More info
Novel inhibitor of DNA-dependent protein kinase (DNA-PK)