Kinase Inhibitors

Dovitinib (TKI-258, CHIR-258) View larger

Dovitinib (TKI-258, CHIR-258)

AOB6730

CAS No:405169-16-6

More details

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$27.00

$27.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.15 Total: $1,215.00
150 $14.04 Total: $702.00
125 $16.47 Total: $411.75
110 $19.44 Total: $194.40
15 $22.95 Total: $114.75

Data sheet

Molecular FormulaC21H21FN6O
Molecular Weight392.43
CAS Numbers405169-16-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO 30 mg/mL (76.44 mM)
Purity98% by HPLC

More info

 A multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays.