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> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>GSK973

Kinase Inhibitors

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GSK973

AOB11511

CAS: 2138473-38-6

 

Chemical Name: (2S,3S)-N5-((1R,5S,6r)-3-oxabicyclo[3.1.0]hexan-6-yl)-2-(fluoromethyl)-N7-methyl-3-phenyl-2,3-dihydrobenzofuran-5,7-dicarboxamide

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $50.15 Total: $250.75
110 $42.48 Total: $424.80
125 $35.99 Total: $899.75
150 $30.68 Total: $1,534.00
1100 $26.55 Total: $2,655.00

Data sheet

Molecular FormulaC23H23FN2O4
Molecular Weight410.45
CAS Numbers2138473-38-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymGSK973; GSK 973; GSK-973
IUPAC/Chemical Name(2S,3S)-N5-((1R,5S,6r)-3-oxabicyclo[3.1.0]hexan-6-yl)-2-(fluoromethyl)-N7-methyl-3-phenyl-2,3-dihydrobenzofuran-5,7-dicarboxamide
InChl KeyWZQLVEPIBAOOGF-RMMWZPCPSA-N
InChl CodeInChI=1S/C23H23FN2O4/c1-25-23(28)15-8-13(22(27)26-20-16-10-29-11-17(16)20)7-14-19(12-5-3-2-4-6-12)18(9-24)30-21(14)15/h2-8,16-20H,9-11H2,1H3,(H,25,28)(H,26,27)/t16-,17+,18-,19+,20+/m1/s1
SMILES CodeO=C(C1=CC(C(NC)=O)=C(O[C@H](CF)[C@H]2C3=CC=CC=C3)C2=C1)N[C@@H]4[C@@]5([H])COC[C@@]45[H]
References1) Alex Presto et al., GSK973 Is an Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family, ACS Med. Chem. Lett. 2020, 11, 8, 1581

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Novel Highly Selective Inhibitor of the Second Bromodomains (BD2s) of the Bromodomain and Extra-Terminal (BET) Family