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Kinase Inhibitors

BRD5648 View larger

BRD5648

AT10608

CAS 2056261-42-6

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$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $45.90 Total: $229.50
110 $38.88 Total: $388.80
125 $32.94 Total: $823.50
150 $28.08 Total: $1,404.00
1100 $24.30 Total: $2,430.00

Data sheet

Molecular FormulaC20H23N3O
Molecular Weight321.42
CAS Numbers2056261-42-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC[C@]1(C2=CNNC2=NC2=C1C(=O)CC(C)(C)C2)c1ccccc1
ReferencesWagner FF, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10[431].

More info

BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705, a GSK3? inhibitor with an IC50 of 66 nM and a Kd of 4.8 ?M, used in acute myeloid leukemia [AML] studies.