Kinase Inhibitors

BC1618 View larger

BC1618

AT8929

CAS 2222094-18-8

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC24H24F3NO2
Molecular Weight415.45
CAS Numbers2222094-18-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(COc1ccc(cc1)C(F)(F)F)CN(Cc1ccccc1)Cc1ccccc1
ReferencesYuan Liu, et al. A Fbxo48 inhibitor prevents pAMPK? degradation and ameliorates insulin resistance. Nat Chem Biol. 2021 Mar;17[3] 298-306.

More info

BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling. It promotes mitochondrial fission, promotes autophagy and improves hepatic insulin sensitivity.