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Kinase Inhibitors
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View larger Ilorasertib
ATQ0059
CAS 1227939-82-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $39.95 | Total: $199.75 |
| 1 | 10 | $33.84 | Total: $338.40 |
| 1 | 25 | $28.67 | Total: $716.75 |
| 1 | 50 | $24.44 | Total: $1,222.00 |
| 1 | 100 | $21.15 | Total: $2,115.00 |
Data sheet
| Molecular Formula | C25H21FN6O2S |
| Molecular Weight | 488.54 |
| CAS Numbers | 1227939-82-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=C2C(=C(C=N1)C3=CN(CCO)N=C3)SC=C2C4=CC=C(NC(NC5=CC(F)=CC=C5)=O)C=C4 |
| References | Gao C, et al. Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase. J Mol Model. 2015 Jul;21[7] 167. |
More info
Ilorasertib (ABT-348) (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora AAurora BAurora C (IC50s: 120 nM7 nM1 nM). It also suppresses RET tyrosine kinase, PDGFR?, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).