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View larger Ilorasertib hydrochloride
AT11638
CAS 1847485-91-9
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C25H22ClFN6O2S |
| Molecular Weight | 525 |
| CAS Numbers | 1847485-91-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Nc1ncc(-c2cnn(CCO)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 |
| References | Glaser KB, et al. Preclinical characterization of ABT-348, a kinase inhibitor targeting the aurora, vascular endothelial growth factor receptorplatelet-derived growth factor receptor, and Src kinase families. J Pharmacol Exp Ther. 2012 Dec;343[3] 617-27. |
More info
Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s: 1 nM, 7 nM, 120 nM). It also suppresses RET tyrosine kinase, PDGFR?, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).