Kinase Inhibitors

Talviraline View larger

Talviraline

AT28918

CAS 163451-80-7

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$111.00

$111.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $49.95 Total: $4,995.00
150 $57.72 Total: $2,886.00
125 $67.71 Total: $1,692.75
110 $79.92 Total: $799.20
15 $94.35 Total: $471.75

Data sheet

Molecular FormulaC15H20N2O3S2
Molecular Weight340.46
CAS Numbers163451-80-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(OC(C)C)(=O)N1C=2C(NC(=S)[C@@H]1CSC)=CC=C(OC)C2
ReferencesDas K, et al. Crystal structures of clinically relevant Lys103AsnTyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097. J Mol Biol. 2007;365[1] 77-89.

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Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human peripheral blood lymphocytes and macrophages.