Kinase Inhibitors

Midostaurin View larger

Midostaurin

AT3211

CAS 120685-11-2

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$40.00

$40.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.00 Total: $1,800.00
150 $20.80 Total: $1,040.00
125 $24.40 Total: $610.00
110 $28.80 Total: $288.00
15 $34.00 Total: $170.00

Data sheet

Molecular FormulaC35H30N4O4
Molecular Weight570.64
CAS Numbers120685-11-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1C(CC2OC1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
ReferencesFabbro D, et al. Pharmacol Ther, 1999, 82[2-3], 293-301.

More info

PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.