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Kinase Inhibitors

dAURK-4 hydrochloride View larger

dAURK-4 hydrochloride

AT74100

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$112.00

$112.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $95.20 Total: $476.00
110 $80.64 Total: $806.40
125 $68.32 Total: $1,708.00
150 $58.24 Total: $2,912.00
1100 $50.40 Total: $5,040.00

Data sheet

Molecular FormulaC52H53Cl2FN8O12
Molecular Weight1071.93
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)NCCCOCCOCCOCCCNC(COC6=CC=CC(C(N7C8C(NC(CC8)=O)=O)=O)=C6C7=O)=O.Cl
ReferencesKatherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183[6] 1714-1731.e10.

More info

dAURK-4 hydrochloride is a selective AURKA (Aurora A) degrader with anticancer and antiproliferative activities. dAURK-4 hydrochloride has been shown to be an anticancer and antiproliferative agent.