Kinase Inhibitors

EF24 View larger

EF24

AT27242

CAS 342808-40-6

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$28.00

$28.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.60 Total: $1,260.00
150 $14.56 Total: $728.00
125 $17.08 Total: $427.00
110 $20.16 Total: $201.60
15 $23.80 Total: $119.00

Data sheet

Molecular FormulaC19H15F2NO
Molecular Weight311.33
CAS Numbers342808-40-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1ccccc1C=C1CNCC(=Cc2ccccc2F)C1=O
ReferencesLelli D, Pedone C, Sahebkar A. Curcumin and treatment of melanoma The potential role of microRNAs. Biomed Pharmacother. 2017 Apr;88 832-834.

More info

EF24 (3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPKERK signaling pathway.