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View larger EML4-ALK kinase inhibitor 1
AT11184
CAS 1373409-08-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $63.75 | Total: $318.75 |
| 1 | 10 | $54.00 | Total: $540.00 |
| 1 | 25 | $45.75 | Total: $1,143.75 |
| 1 | 50 | $39.00 | Total: $1,950.00 |
| 1 | 100 | $33.75 | Total: $3,375.00 |
Data sheet
| Molecular Formula | C31H48N8O3 |
| Molecular Weight | 580.76 |
| CAS Numbers | 1373409-08-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1N[C@H]1CC[C@@H](CC1)OC |
| References | Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 [EML4]-anaplastic lymphoma kinase [ALK] inhibitors. Bioorg Med Chem. 2019 Apr 15;27[8] 1683-1692. |
More info
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.