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View larger Lerociclib dihydrochloride
AT11345L
CAS 2097938-59-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Data sheet
| Molecular Formula | C26H36Cl2N8O |
| Molecular Weight | 547.52 |
| CAS Numbers | 2097938-59-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.CC(C)N1CCN(CC1)c1ccc(Nc2ncc3cc4C(=O)NCC5(CCCCC5)n4c3n2)nc1 |
| References | Bisi JE, et al. Preclinical development of G1T38 A novel, potent and selective inhibitor of cyclin dependent kinases 46 for use as an oral antineoplastic in patients with CDK46 sensitive tumors. Oncotarget. 2017 Jun 27;8[26] 42343-42358. |
More info
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective CDK4CDK6 inhibitor, with IC50 values of 2 nM for CDK6CyclinD3 and 1 nM for CDK4CyclinD1.