Kinase Inhibitors

Nemiralisib View larger

Nemiralisib

AT15431

CAS 1254036-71-9

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$34.00

$34.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.30 Total: $1,530.00
150 $17.68 Total: $884.00
125 $20.74 Total: $518.50
110 $24.48 Total: $244.80
15 $28.90 Total: $144.50

Data sheet

Molecular FormulaC26H28N6O
Molecular Weight440.54
CAS Numbers1254036-71-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)N1CCN(Cc2cnc(o2)-c2cc(cc3[nH]ncc23)-c2cccc3[nH]ccc23)CC1
ReferencesDown K et al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase ? for the Treatment of Respiratory Disease. J Med Chem. 2015 Sep 24;58[18] 7381-99.

More info

Nemiralisib?GSK-2269557 free base? is an orally available, potent and specific PI3K? inhibitor with a pKi of 9.9.Nemiralisib is used for the treatment of respiratory diseases including chronic obstructive pulmonary disease.