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View larger GSK872 HCl?1346546-69-7 free base?
AT4074L
CAS 2703752-81-0
Molarity Calculation Cart®
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $11.70 | Total: $1,170.00 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 5 | $22.10 | Total: $110.50 |
Data sheet
| Molecular Formula | C19H18ClN3O2S2 |
| Molecular Weight | 419.94 |
| CAS Numbers | 2703752-81-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CC(C)S(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1 |
| References | Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014, 56[4] 481-95. |
More info
GSK872 HCl?1346546-69-7 free base? (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).