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View larger H-1152 dihydrochloride
AT35328
CAS 871543-07-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $41.65 | Total: $208.25 |
| 1 | 10 | $35.28 | Total: $352.80 |
| 1 | 25 | $29.89 | Total: $747.25 |
| 1 | 50 | $25.48 | Total: $1,274.00 |
| 1 | 100 | $22.05 | Total: $2,205.00 |
Data sheet
| Molecular Formula | C16H23Cl2N3O2S |
| Molecular Weight | 392.34 |
| CAS Numbers | 871543-07-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12 |
| References | Tamura M, et al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30;1754[1-2] 245-52. Epub 2005 Sep 12. |
More info
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 ?M, 5.68 ?M, 0.360 ?M, 0.745 ?M and 0.180 ?M, respectively.