Kinase Inhibitors

IHMT-PI3K?-372 View larger

IHMT-PI3K?-372

AT35530

CAS 2429889-62-1

More details

Molarity Calculation Cart®

HOW TO ORDER

$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.55 Total: $1,755.00
150 $20.28 Total: $1,014.00
125 $23.79 Total: $594.75
110 $28.08 Total: $280.80
15 $33.15 Total: $165.75

Data sheet

Molecular FormulaC26H23F2N7O2
Molecular Weight503.5
CAS Numbers2429889-62-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC[C@H](c1nc2cccc(F)c2c(=O)n1C1CC1)n1nc(-c2ccc(OC)c(F)c2)c2c(N)ncnc12
ReferencesFeng Li, et al. Discovery of [S]-2-[1-[4-Amino-3-[3-fluoro-4-methoxyphenyl]-1 H-pyrazolo[3,4- d]pyrimidin-1-yl]propyl]-3-cyclopropyl-5-fluoroquinazolin-4[3 H]-one [IHMT-PI3K?-372] as a Potent and Selective PI3K? Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease. J Med Chem. 2020 Nov 25;63[22] 13973-13993.

More info

IHMT-PI3K?-372 is a selective inhibitor of PI3K? with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.