Kinase Inhibitors

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ACHP

AT22021

CAS 406208-42-2

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC21H24N4O2
Molecular Weight364.44
CAS Numbers406208-42-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN#CC1=C(N=C(C=C1C2CCNCC2)C=3C(O)=CC=CC3OCC4CC4)N
ReferencesPandur, E., et al. Anti-inflammatory effect of lavender [Lavandula angustifolia Mill.] essential oil prepared during different plant phenophases on THP-1 macrophages. BMC Complement Med Ther 21, 287 [2021].

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ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-? and IKK-?. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression through inhibition of NF-?B activation, inhibits TNF-?-induced NF-?B (p65) recruitment to the HIV-1 LTR, and inhibits TNF-?-induced NF-?B (p65) recruitment to the HIV-1 LTR. ACHKP has anti-HIV-1 activity and inhibits TNF-?-induced recruitment of NF-?B (p65) to the HIV-1 LTR.