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View larger Prexasertib dihydrochloride
AT4327
CAS 1234015-54-3
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Data sheet
| Molecular Formula | C18H21Cl2N7O2 |
| Molecular Weight | 438.31 |
| CAS Numbers | 1234015-54-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1 |
| References | Hong D,etal.Phase I Study of LY2606368, a Checkpoint Kinase 1 Inhibitor, in Patients With Advanced Cancer.J Clin Oncol. 2016 May 20;34[15] 1764-71. |
More info
Prexasertib dihydrochloride (LY2606368) is an ATP-competitive CHK1 inhibitor (Ki: 0.9 nmolL). in the cell-free assay, its IC50 values are 8 nM and 9 nM for CHK2 and RSK, respectively.