Kinase Inhibitors

PD 407824 View larger

PD 407824

AT16446

CAS 622864-54-4

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$59.00

$59.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $26.55 Total: $2,655.00
150 $30.68 Total: $1,534.00
125 $35.99 Total: $899.75
110 $42.48 Total: $424.80
15 $50.15 Total: $250.75

Data sheet

Molecular FormulaC20H12N2O3
Molecular Weight328.32
CAS Numbers622864-54-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1
ReferencesPalmer BD, et al. 4-Phenylpyrrolo[3,4-c]carbazole-1,3[2H,6H]-dione inhibitors of the checkpoint kinase WeeStructure-activity relationships for chromophore modification and phenyl ring substitution. J Med Chem. 2006 Aug 10;49[16] 4896-911.

More info

PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).