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View larger PF-3758309 hydrochloride
AT4230
CAS 1279034-84-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Data sheet
| Molecular Formula | C25H31ClN8OS |
| Molecular Weight | 527.08 |
| CAS Numbers | 1279034-84-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)n[nH]c2C1(C)C)c1ccccc1 |
| References | Briz V, Baudry M. Estrogen Regulates Protein Synthesis and Actin Polymerization in Hippocampal Neurons through Different Molecular Mechanisms. Front Endocrinol [Lausanne]. 2014 Feb 25;5 22. doi 10.3389fendo.2014.00022. eCollection 2014. PubMed PMID 24611062; PubMed Central PMCID PMC3933789. |
More info
PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. PF-3758309 hydrochloride binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serinethreonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.