Kinase Inhibitors

Tipranavir View larger

Tipranavir

AT4578

CAS 174484-41-4

More details

Molarity Calculation Cart®

HOW TO ORDER

$106.00

$106.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $47.70 Total: $4,770.00
150 $55.12 Total: $2,756.00
125 $64.66 Total: $1,616.50
110 $76.32 Total: $763.20
15 $90.10 Total: $450.50

Data sheet

Molecular FormulaC31H33F3N2O5S
Molecular Weight602.66
CAS Numbers174484-41-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1
ReferencesAoki M, et al. Loss of the protease dimerization inhibition activity of tipranavir [TPV] and its association with the acquisition of resistance to TPV by HIV-J Virol. 2012 ; 86[24] 13384-13396.

More info

Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity.