Kinase Inhibitors

SP-141 View larger

SP-141

AT21773

CAS 1253491-42-7

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC22H16N2O
Molecular Weight324.38
CAS Numbers1253491-42-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc2[nH]c3c(nccc3c2c1)-c1cccc2ccccc12
ReferencesWei Wang, et al. The Pyrido[b]indole MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer Models. Nat Commun. 2014 Oct 1;5 5086.

More info

SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.