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View larger TAK-659 hydrochloride
AT4209
CAS 1952251-28-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $12.60 | Total: $1,260.00 |
| 1 | 50 | $14.56 | Total: $728.00 |
| 1 | 25 | $17.08 | Total: $427.00 |
| 1 | 10 | $20.16 | Total: $201.60 |
| 1 | 5 | $23.80 | Total: $119.00 |
Data sheet
| Molecular Formula | C17H22ClFN6O |
| Molecular Weight | 380.85 |
| CAS Numbers | 1952251-28-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12 |
| References | Lam B, et al. Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase [SYK]. Bioorg Med Chem Lett. 2016 Dec 15;26[24] 5947-5950. |
More info
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.