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Kinase Inhibitors
- Protein Control Ligand
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View larger XY028-140
AT36694
CAS 2229974-83-6
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Data sheet
| Molecular Formula | C39H40N10O7 |
| Molecular Weight | 760.8 |
| CAS Numbers | 2229974-83-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)N4CCN(C(CNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)=O)CC4)N2)C8CCCC8 |
| References | Jian Jin, et al. Compositions and methods for treating cdk46-mediated cancer. WO2018106870A1. |
More info
XY028-140 is a selective CDK4CDK6 degrade and inhibits both CDK46 expression and activity in cancer cells. XY028-140 is a PROTAC connected by ligands for Cereblon and CDK.