Kinase Inhibitors

BAY-985 View larger

BAY-985

AT10477

CAS 2409479-29-2

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$149.00

$149.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $67.05 Total: $6,705.00
150 $77.48 Total: $3,874.00
125 $90.89 Total: $2,272.25
110 $107.28 Total: $1,072.80
15 $126.65 Total: $633.25

Data sheet

Molecular FormulaC27H30F3N9O
Molecular Weight553.58
CAS Numbers2409479-29-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@H](N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cc(ncn2)N(C)C)c1
ReferencesLefranc J, et al. Discovery of BAY-985, a Highly Selective TBK1IKK? Inhibitor. J Med Chem. 2020 Jan 10.

More info

BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKK? (IC50s: 230 and 2 nM for TBK1 (lowhigh ATP) and IKK?) with antitumor efficacy.