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Kinase Inhibitors

CCT241533 hydrochloride View larger

CCT241533 hydrochloride

AT10718L

CAS 1431697-96-9

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$57.00

$57.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $48.45 Total: $242.25
110 $41.04 Total: $410.40
125 $34.77 Total: $869.25
150 $29.64 Total: $1,482.00
1100 $25.65 Total: $2,565.00

Data sheet

Molecular FormulaC23H28ClFN4O4
Molecular Weight478.95
CAS Numbers1431697-96-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.COc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O
ReferencesAnderson VE, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 2011 Jan 15;71[2] 463-72.

More info

CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).