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Kinase Inhibitors

CDK9-IN-7 View larger

CDK9-IN-7

AT10745

CAS 2369981-71-3

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$100.00

$100.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $85.00 Total: $425.00
110 $72.00 Total: $720.00
125 $61.00 Total: $1,525.00
150 $52.00 Total: $2,600.00
1100 $45.00 Total: $4,500.00

Data sheet

Molecular FormulaC29H37N7O2S
Molecular Weight547.71
CAS Numbers2369981-71-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(N(C)C)(=O)C=1N(C=2C(C1)=CN=C(NC3=CC=C(NC(CCCCCCCN=C=S)=O)C=C3)N2)C4CCCC4
ReferencesWang X, et al. Novel cyclin-dependent kinase 9 [CDK9] inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer. Eur J Med Chem. 2019 Jul 25;181 111535.

More info

CDK9-IN-7 is a highly selective and orally active CDK9cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4cyclinD: 148 nM; CDK6cyclinD: 145 nM).