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View larger DHODH-IN-4
AT11027
CAS 1148125-93-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Data sheet
| Molecular Formula | C17H12Cl2N2O2 |
| Molecular Weight | 347.2 |
| CAS Numbers | 1148125-93-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | ClC1=C(C2=CC(Cl)=C(NC(C(=C(C)O)C#N)=O)C=C2)C=CC=C1 |
| References | Davies M, et al. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52[9] 2683-93. |
More info
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 ?M and 0.18 ?M, respectively. DHODH-IN-4 has antimalarial activity.