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View larger GSK2983559 free acid
AT11492
CAS 1579965-12-0
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HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.50 | Total: $1,350.00 |
| 1 | 50 | $15.60 | Total: $780.00 |
| 1 | 25 | $18.30 | Total: $457.50 |
| 1 | 10 | $21.60 | Total: $216.00 |
| 1 | 5 | $25.50 | Total: $127.50 |
Data sheet
| Molecular Formula | C21H23N4O7PS2 |
| Molecular Weight | 538.53 |
| CAS Numbers | 1579965-12-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1C2=C(C=C(OCCOP(=O)(O)O)C(S(C(C)(C)C)(=O)=O)=C2)N=CN1)C=3C=C4C(=CC3)SC=N4 |
| References | Haile PA, et al. Discovery of a First-in-Class Receptor Interacting Protein 2 [RIP2] Kinase Specific Clinical Candidate, 2-[[4-[Benzo[d]thiazol-5-ylamino]-6-[tert-butylsulfonyl]quinazolin-7-yl]oxy]ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. J Med Chem. 2019 Jul 25;62[14] 6482-6494. |
More info
GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an