Kinase Inhibitors

N-piperidine Ibrutinib hydrochloride View larger

N-piperidine Ibrutinib hydrochloride

AT12152

CAS 2231747-18-3

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC22H23ClN6O
Molecular Weight422.91
CAS Numbers2231747-18-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCNCC1
ReferencesBuhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57[26] 3564-3575.

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N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor, a BTK ligand, inhibits WT BTK and C481S BTK, which can be used to synthesize a range of PROTAC molecules.N-piperidine Ibrutinib hydrochloride has potential anticancer N-piperidine Ibrutinib hydrochloride has potential anticancer activity, inhibiting the growth and proliferation of cancer cells.