Kinase Inhibitors

NMS-P715 View larger

NMS-P715

AT12237

CAS 1202055-32-0

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$61.00

$61.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $27.45 Total: $2,745.00
150 $31.72 Total: $1,586.00
125 $37.21 Total: $930.25
110 $43.92 Total: $439.20
15 $51.85 Total: $259.25

Data sheet

Molecular FormulaC35H39F3N8O3
Molecular Weight676.73
CAS Numbers1202055-32-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCc1cccc(CC)c1NC(=O)c1nn(C)c-2c1CCc1cnc(Nc3ccc(cc3OC(F)(F)F)C(=O)NC3CCN(C)CC3)nc-21
ReferencesColombo R, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010 Dec 15;70[24] 10255-64.

More info

NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).