Kinase Inhibitors

PI3K?-IN-1 View larger

PI3K?-IN-1

AT12462

CAS 1911564-39-0

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$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC22H20F3N7O2
Molecular Weight471.44
CAS Numbers1911564-39-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(=O)N1CCN(C(=O)C1(C)C)c1cc(ccc1C#N)-c1cc(c2c(N)ncnn12)C(F)(F)F
ReferencesLiu Q, et al. Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase ? [PI3K?] Inhibitor for the Treatment of Immunological Disorders. J Med Chem. 2017 Jun 22;60[12] 5193-5208.

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PI3K?-IN-1 is an efficacious PI3K? inhibitor (IC50 of 1.7 nM).